Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst

Authors

Affiliations

Claire S. Simon

University of Cambridge

Kathy K. Niakan

Babraham Institute

University of Cambridge

Wellcome/MRC Cambridge Stem Cell Institute

The Francis Crick Institute

Laura Woods

University of Cambridge

Alex Faulkner

Newcastle upon Tyne Hospitals NHS Foundation Trust

Martin Proks

Novo Nordisk Foundation

University of Copenhagen

Nazmus Salehin

Novo Nordisk Foundation

University of Copenhagen

Georgia Lea

The Loke Centre for Trophoblast Research

University of Cambridge

Madeleine Linneberg-Agerholm

Novo Nordisk Foundation

University of Copenhagen

Joshua M. Brickman

Novo Nordisk Foundation

University of Copenhagen

Abstract

Processed embryo scRNAseq data

Files

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DOI:10.5281/zenodo.15128175

Papers

Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
DOI:10.1038/s41467-025-61830-x