Aberrant gene expression leakage from lineage-specific heterochromatic loci during senescence

sequencing
Abstract
To understand induction of cornification genes on lineage appropriate (keratinocyte differentiation) and inappropriate (fibroblast senescence) conditions , we generated histone modification and gene expression dataset. Then we compared these keratinocyte’s dataset with our previous fibroblast senescence dataset in the study.

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GEO:GSE130457

Papers

Locus-specific induction of gene expression from heterochromatin loci during cellular senescence
DOI:10.1038/s43587-021-00147-y