Aberrant gene expression leakage from lineage-specific heterochromatic loci during senescence

sequencing
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Abstract
To understand induction of cornification genes during lineage appropriate (keratinocyte differentiation) and inappropriate (fibroblast senescence) conditions, we generated histone modification and gene expression datasets. Then we compared keratinocyte’s datasets with fibroblast senescence ones in this study.

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GEO:GSE180469

Papers

Locus-specific induction of gene expression from heterochromatin loci during cellular senescence
DOI:10.1038/s43587-021-00147-y