nf-fgwas

Abstract
Nextflow implementation of fGWAS for single cell data. The pipeline uses the hierarchical model from here and the application to single cell data has been described in detail here. In brief, given a single cell dataset and GWAS summary statistics, fGWAS allows to find cell types that are enriched for the genetic associations. It requires full GWAS summary statistics, including logOR and standard error.

Files

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SWHID:swh:1:dir:521f5ebc748f098312488a3cff71a7a9124bda50

Papers

A multi-omic atlas of human embryonic skeletal development
DOI:10.1038/s41586-024-08189-z